报告题目: Vesicle-mediated Secretion of Specific Antigens of the Human Pathogen Babesia microti Into the Mammalian Host

报告人:  Choukri Ben Mamoun博士，副教授

报告地点: 动医动科楼401会议室

报告时间: 6月21日（星期四）下午15: 00-17: 30

联系人: 索 勋  教授

报告人简介: Choukri Ben Mamoun博士，美国 “常青藤联盟”成员、 “常春藤盟校”成员---校耶鲁大学（Yale University）副教授。曾任PLoS Pathogens专业杂志副主编（2007），Nature Scientific Reports（2017）、Journal of Biological Chemistry杂志编委，eLife审稿编辑（2017），Cell、Nature、PNAS等杂志同行评阅人。研究兴趣为抗寄生虫药物的研制及其作用机理。研究成果累计发表发表SCI研究论文70余篇和特邀研究综述及评论数篇。

部分研究论文：

Azan Z. Virji, Jose Thekkiniath, Wenxiu Ma, Lauren Lawres, James Knight, Andrea Swei, Karine Le Roch, Choukri, Ben Mamoun. Insights into evolution and drug susceptibility of Babesia duncani from the sequence of its mitochondrial and apicoplast genomes. Int. J. Parasitology. 2018. In press

Jae-Yeon Choi, Yulia V. Surovtseva, Sam M. Van Sickle, Jan Kumpf, Uwe H. F. Bunz, Choukri Ben Mamoun, and Dennis R. Voelker. A Novel Fluorescence Assay for Measuring Phosphatidylserine Decarboxylase Activity in vitro. J. Biol. Chem. 2018. doi: 10.1074/jbc.RA117.000525. PMID:2924700

Lauren Lawres, Aprajita Garg, Vidya Kumar, Igor Bruzual, Isaac P. Forquer, Isaline Renard, Azan Virji, Pierre Boulard, Eduardo X. Rodriguez, Alexander J. Allen, Sovitj Pou, Keith W. Wegmann, Rolf W. Winter, Aaron Nilsen, Jialing Mao, Douglas A. Preston, Alexia A. Belperron, Linda K. Bockenstedt, David J. Hinrichs, Michael K. Riscoe, J.Stone Doggett and Choukri Ben Mamoun. Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone. J. Exp. Med. 2016. PMID: 27270894

Bobenchik, A.M., Witola, W.H., Augagneur, A., Nic Lochlainn, Garg, A., Pachikara, N., Choi, J., Zhao, Y.O., Usmani-Brown, S., Lee, A., L., Adjalley, S.H., Samanta, S., Fidock, D.A., Voelker, D., Fikrig, E. and Ben Mamoun, C. Essential role of the malarial PfPMT methyltransferae in gametocyte maturation. Proc. Natl. Acad. Sci. U S A. 2013; 110(45): 18262-7. PubMed PMID: 24145416; PubMed Central PMCID: PMC3831454.

欢迎老师和同学参加！